8/19/22
Pharmacogenetics: the ability for scientists to look at someone's genes and predict how they will react to a certain drug.
Side effects: caused by a medicine binding to a variety of receptors and/or on different cells.
Between 5-10% of patients experience adverse side effects (ADRs).
Rebound effect: the worsening of previous symptoms after a drug has been stopped. This leads to a vicious cycle of being prescribed a higher dose to control the symptoms, experiencing rebound, and re-prescribing again. SOLUTION: tapering down a medication instead of stopping it cold-turkey.
1/3 of hospital stays are extended because inappropriate medications are given to patients, or managed improperly by medical staff.
A dose of a drug is determined by the following: 1.) person's body size, 2.) how rapidly the drug breaks down and is eliminated, 3.) sometimes by the presence of food/drugs that are recently consumed. 4.) any placebo effect, 5.) a person's mental state (example: patient needing more analgesic meds because they are anxious).
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